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BrennerBot
Operationalizing Sydney Brenner's scientific methodology through multi-agent collaboration. Extract wisdom from the master, apply it to your domain.
What's Inside
A research toolkit for applying Brenner's epistemology to your own scientific questions.
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Corpus
The complete Brenner transcript collection from Web of Stories, plus curated quote banks and metaprompts.
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Distillations
Three frontier model distillations of Brenner's methodology. Compare perspectives from GPT-5.2, Opus 4.5, and Gemini 3.
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Method
The operators, loop structure, and Bayesian framework that operationalize Brenner's approach to scientific discovery.
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236
Interview Segments
3
Model Distillations
12+
Operator Types
40k+
Words of Wisdom
“I think many fields of science could do a great deal better if they went back to the classical approach of studying a problem, rather than following the latest fashion.